A monthly publication of the Brazilian Society of Cardiology and considered the main channel for the promotion of Brazilian cardiovascular research.
ISSN 0066-782X
eISSN 1678-4170
Edmar Atik
, Gabriela Nunes Leal, Marcelo B. Jatene
Edmar Atik
, Gabriela Nunes Leal, Marcelo B. Jatene
Introduction Hypertrophic cardiomyopathy (HCM), characterized by hypertrophy of the left ventricle, has no etiological explanation under conditions of the usual diseases that cause cardiac overloads like systemic arterial hypertension, obstructive congenital heart diseases, and other pathologies. – It results from cardiovascular genetic pathology causing a complex disease, from gene diversity (more than 1400 mutations identified in 11 different genes) to phenotypic expression, histological characteristics, and manifested symptoms. Beta myosins (MYH7) genes occur in 35% of the cases, and myosin is […]
Keywords: Abnormalities Congenital/surgery; Cardiomyopathy, Hypertrophic/surgery; Diagnostic, Imaging/methods; Hypertrophy, Left Ventricular/surgery; Risk Factors; Sudden Cardiac Death