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A monthly publication of the Brazilian Society of Cardiology and considered the main channel for the promotion of Brazilian cardiovascular research.
ISSN 0066-782X
eISSN 1678-4170
Filipe Ferrari, Ricardo Stein, Marcelo Trotte Motta, Emilio Hideyuki Moriguchi
Filipe Ferrari, Ricardo Stein, Marcelo Trotte Motta, Emilio Hideyuki Moriguchi
DOI: 10.5935/abc.20190029
Coronary artery disease (CAD) is one of the leading causes of mortality. High circulating levels of low-density lipoprotein (LDL) in the blood are associated with cardiovascular mortality, whether through an etiological role or through its association with the progression of CAD per se. Randomized clinical trials have shown that, when LDL levels are reduced, cardiovascular risk is also reduced, which reinforces this association. The first major trial involving a hypolipidemic agent of the statin family, the Scandinavian Simvastatin Survival Study […]
Keywords: Anticholesteromic Agents; Cardiovascular Diseases/physiopathology; Cholesterol, LDL; Coronary Artery Disease/mortality; Lipoproteins; Proprotein Convertase 9