In recent decades, the epidemiology of Chagas disease (Chd) has changed significantly as a consequence of urbanization and migration. In Brazil, to date, it is the neglected disease with the highest burden, of which ~30% of individuals will progress to the symptomatic tissue disruptive stage within 20 – 30 years after being infected (around 2% per year progress from the indeterminate to the cardiac form, according to a contemporary study). Persistent myocardial inflammation and fibrosis represent the main pathological characteristics […]