A monthly publication of the Brazilian Society of Cardiology and considered the main channel for the promotion of Brazilian cardiovascular research.
ISSN 0066-782X
eISSN 1678-4170
Tarley Santos Oliveira, Igor Smirnow
, Kadija Mohamed Santee, Maria Angelica Miglino
, Rodrigo da Silva Nunes Barreto
Tarley Santos Oliveira, Igor Smirnow
, Kadija Mohamed Santee, Maria Angelica Miglino
, Rodrigo da Silva Nunes Barreto
Background Objectives The present project aims to achieve the artificial development of blood vessels through the recellularization of vascular scaffolds derived from bovine placental vessels. Methods The chorioallantoic surface of the bovine placenta was used to produce decellularized biomaterials. For recellularization, 2.5 x 104 endothelial cells were seeded above each decellularized vessel fragment during three or seven days, when culture were interrupted, and the fragments were fixed for cell attachment analysis. Decellularized and recellularized biomaterials were evaluated by basic histology, […]
Keywords: Bioengineering; Blood Vessels; Decellularized Extracellular Matrix
Leonardo Rufino Garcia
, André Monti Garzesi, Flávio de Souza Brito
, Marcello Laneza Felicio, Matheus Bertanha
Leonardo Rufino Garcia
, André Monti Garzesi, Flávio de Souza Brito
, Marcello Laneza Felicio, Matheus Bertanha
Background Objectives The present project aims to achieve the artificial development of blood vessels through the recellularization of vascular scaffolds derived from bovine placental vessels. Methods The chorioallantoic surface of the bovine placenta was used to produce decellularized biomaterials. For recellularization, 2.5 x 104 endothelial cells were seeded above each decellularized vessel fragment during three or seven days, when culture were interrupted, and the fragments were fixed for cell attachment analysis. Decellularized and recellularized biomaterials were evaluated by basic histology, […]
Keywords: Biocompatible Materials; Blood Vessels; Cardiovascular Diseases; Cell Nucleous (Scaffold; Mortality; Stem Cells; Tissue Engineering, Bioengineering/trends