A monthly publication of the Brazilian Society of Cardiology and considered the main channel for the promotion of Brazilian cardiovascular research.
ISSN 0066-782X
eISSN 1678-4170
Karine Ferreira da Silva Carvalho, Amanda Araújo Marques Ferreira, Nayara Carvalho Barbosa, Juliano Vilela Alves, Rafael Menezes da Costa
Karine Ferreira da Silva Carvalho, Amanda Araújo Marques Ferreira, Nayara Carvalho Barbosa, Juliano Vilela Alves, Rafael Menezes da Costa
Abstract Background Metabolic syndrome is characterized by an array of comorbidities. During this syndrome, structural changes are observed in the cardiovascular system, especially vascular remodeling. One of the predisposing causes for these changes is chronic inflammation resulting from changes in the structure and composition of perivascular adipose tissue. Atorvastatin is effective in the treatment of dyslipidemias. However, its pleiotropic effects have not been completely understood. We hypothesize that metabolic syndrome may lead to vascular remodeling and that atorvastatin therapy may […]
Keywords: Atorvastatin; Dietary Carbohydrates; Dyslipidemias; Inflammation; Metabolic Syndrome; Mice; Vascular Remodeling
Silvio A. Oliveira-Junior
, Marianna R. Carvalho
, Maria Lua M Mendonça
, Paula F. Martinez
Silvio A. Oliveira-Junior
, Marianna R. Carvalho
, Maria Lua M Mendonça
, Paula F. Martinez
Abstract Background Metabolic syndrome is characterized by an array of comorbidities. During this syndrome, structural changes are observed in the cardiovascular system, especially vascular remodeling. One of the predisposing causes for these changes is chronic inflammation resulting from changes in the structure and composition of perivascular adipose tissue. Atorvastatin is effective in the treatment of dyslipidemias. However, its pleiotropic effects have not been completely understood. We hypothesize that metabolic syndrome may lead to vascular remodeling and that atorvastatin therapy may […]
Keywords: Abdominal Obesity; Atorvastatin/drug therapy; Diabetes Mellitus; Endothelium/etiology; Hypertension; Inflammation; Inflammation, Prognostic; Metabolic Syndrome; Metabolism Syndrome; Obesity, Abdominal