Introduction Annually the Revista Portuguesa de Cardiologia (RPC) and the Arquivos Brasileiros de Cardiologia (ABC) have gathered to elaborate a special article with the selection of their best original publications.– Over the years, the high quality of their papers has become clear, evidencing the dynamism of cardiovascular investigation in Portuguese-speaking countries. Following tradition, the editorial bodies of the RPC and the ABC met once again to select the ten best articles published in 2021 by each of those journals ( […]