Abstract Infective endocarditis in the pediatric population is a rare condition that may or may not be associated with a congenital heart disease. Current treatment modalities are based on long-term antibiotic therapy and surgical resection as the first option for cases of persistent vegetation. We present a case of successful percutaneous retrieval of a vegetation in a patent ductus arteriosus, that extended to the pulmonary artery trunk in a pediatric patient. This is the first report in the literature on […]

Introduction Cancer patients are prone to infective endocarditis (IE), associated with specific causative agents, leading to poorer outcomes. The prevalence of IE in cancer patients ranges from 5.6% to 18%, with a reported 1-year mortality rate of nearly 30%. – Risk factors, such as a suppressed immune system, intravascular catheter use, and hypercoagulability, predispose malignancy patients to IE. , Clinical evolution is unfavorable due to high mortality rates related to antibiotic resistance, underlying medical conditions, lack of performed surgical interventions, […]

Introduction Coxiella burnetii infective endocarditis (IE) represents a rarely reported zoonosis in Brazil. It is estimated that Coxiella burnetii is responsible for up to 5% of all IE cases worldwide. The disease affects mostly valvulopathy patients and immunocompromised subjects. Different from the classical acute and sub-acute endocarditis, the clinical picture is frustrating, and, because this is an obligate intracellular microorganism, hemocultures (HMC) are predominantly negative, which makes the clinical suspicion more difficult. […]

Introduction Infectious endocarditis (IE) is a serious disease with a mean in-hospital mortality of 20%. – It has shown an increasing incidence, and the rise in its prevalence among the elderly population deserves to be highlighted. – In elderly patients with IE, there are differences regarding the clinical presentation, complications, presence of comorbidities, therapeutic approach and mortality. , – IE guidelines do not specifically address the elderly population and it is not clear to what extent they can be appropriately […]

Background: Neurological complications are common in patients with infective endocarditis (IE). Recent data suggest that neurologic events are a major determinant of prognosis, and that surgery is critical in improving the outcome. Objective: To characterize patients with IE and neurological complications and to determine predictors of embolization to the central nervous system (CNS) and mortality. Methods: Retrospective analysis of patients admitted to a tertiary center with the diagnosis of IE from 2006 to 2016. Statistical significance was defined by a […]

Abstract Background In recent years, the incidence of infections related to cardiac implantable electronic devices (CIED) has increased sharply, impacting mortality. Objective To verify the proportion of patients with CIED infection; to analyze their clinical profile and the variables related to the infection and its progression. Methods Retrospective and longitudinal observational study including 123 patients with CIED infection among 6406 procedures. Parametric tests and a level of significance of 5% were used in the statistical analyses Results The mean age […]

Introduction The Bentall procedure was described for the first time 50 years ago and has undergone several improvements through the years. This technique is considered to be a longstanding and safe procedure. However, as any surgery, it can have several complications such as anastomotic pseudoaneurism, myocardial infarction and endocarditis. In developed countries with differentiated access to health care and prophylaxis, endocarditis is an uncommon pathology, associated to frequent complications and high mortality rates. Antibiotic therapy aims to eradicate the responsible […]

Abstract We present a case report of a patient with an infected mitral valve myxoma and a literature review on the subject. A 33-year-old female presented with a history of fever and dyspnea evolving over a few days. On admission, she had a lupus-like syndrome with positive blood cultures for Haemophilus species . Echocardiogram revealed a giant mass involving both mitral leaflets causing severe regurgitation, requiring biological mitral valve replacement. Microscopy showed an infected myxoma and the patient was discharged […]