Coronary artery disease (CAD) is a leading cause of death worldwide. It is most commonly caused by atherosclerosis in coronary arteries. Coronary artery disease has a complex etiology, mainly a combination of traditional risk factors and genetic predisposition. Traditional risk factors include type 2 diabetes, dyslipidemia, arterial hypertension, and cigarette smoking. However, these are not sufficient to identify high risk asymptomatic individuals and do not explain all cases of CAD. In fact, hereditary influence on CAD susceptibility accounts for between […]