Introduction Depression is a global disease affecting around 330 million people, corresponding to 4.4% of the global population, and is the second cause of incapacitation in the USA. In Brazil, it is estimated that 5.8% of the population, 11 million people, suffer from this disease, placing the country first in Latin America and the second in the Americas considering the number of cases. In addition, the data published by the National Health Survey (PNS) conducted in 2013 verified that 78.8% […]

Abstract Background: Stress is defined as a complicated state that related to homeostasis disturbances, over-activity of the sympathetic nervous system and hypothalamus-pituitary-adrenal axis responses. Cardiac preconditioning reduces myocardial damages. Objective: This study was designed to assess the cardioprotective effects of acute physical stress against ischemia/reperfusion (I/R) injury through the activation of the sympathetic nervous system. Methods: Thirty-two male Wistar rats were divided into four groups; (1) IR (n = 8): rats underwent I/R, (2) Acute stress (St+IR) (n = 8): […]