A monthly publication of the Brazilian Society of Cardiology and considered the main channel for the promotion of Brazilian cardiovascular research.
ISSN 0066-782X
eISSN 1678-4170
Fábio Fernandes
, Dirceu Thiago Pessoa de Melo
, Felix José Alvarez Ramires, Ester Cerdeira Sabino, Carlos Henrique Valente Moreira
, [...]
Fábio Fernandes
, Dirceu Thiago Pessoa de Melo
, Felix José Alvarez Ramires, Ester Cerdeira Sabino, Carlos Henrique Valente Moreira
, [...]
Abstract Background Galectin-3 (Gal-3) is a proinflammatory, profibrotic molecule implicated in the pathogenesis of heart failure. The role of Gal-3 in patients with chronic constrictive pericarditis (CCP) is not clear. Objective The aim of this study was to assess plasma Gal-3 in patients with CCP and correlate it with clinical, functional and histologic parameters. Methods We prospectively evaluated 25 symptomatic patients with CCP referred for pericardiectomy and 21 healthy controls. Patients underwent clinical assessment, Gal-3 and B-type natriuretic peptide (BNP) […]
Keywords: Cell Diferentiation; Fibrosis; Galectin 3; Pericardiectomy/methods; Pericardite Constrictive/surgery
Abstract Background Galectin-3 (Gal-3) is a proinflammatory, profibrotic molecule implicated in the pathogenesis of heart failure. The role of Gal-3 in patients with chronic constrictive pericarditis (CCP) is not clear. Objective The aim of this study was to assess plasma Gal-3 in patients with CCP and correlate it with clinical, functional and histologic parameters. Methods We prospectively evaluated 25 symptomatic patients with CCP referred for pericardiectomy and 21 healthy controls. Patients underwent clinical assessment, Gal-3 and B-type natriuretic peptide (BNP) […]
Keywords: Biomarkers; Cardiomyopathy, Restrictive; Galectin 3; Inflammation; Pericarditis Constrictive; Pericardium