A monthly publication of the Brazilian Society of Cardiology and considered the main channel for the promotion of Brazilian cardiovascular research.
ISSN 0066-782X
eISSN 1678-4170
Julio Gil, Bruno Marmelo, Luís Abreu, Hugo Antunes, Luís Ferreira dos Santos, [...]
Julio Gil, Bruno Marmelo, Luís Abreu, Hugo Antunes, Luís Ferreira dos Santos, [...]
DOI: 10.5935/abc.20180033
Introduction Propafenone is a class IC antiarrhythmic drug used in the treatment of ventricular and supraventricular arrhythmias.– It is primarily a potent sodium channel blocker, yet also exhibits beta-blocking and calcium channel blocking activity.,, Propafenone is able to induce important ECG changes, namely prolongation of the PR interval, bundle branch block, wide QRS and QT intervals, as well as ventricular tachycardia or bradycardia., It may be associated with significant proarrhythmogenic effects, even at therapeutic doses. A fatal overdose on propafenone […]
Keywords: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Propafenone; Toxicity