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A monthly publication of the Brazilian Society of Cardiology and considered the main channel for the promotion of Brazilian cardiovascular research.
ISSN 0066-782X
eISSN 1678-4170
Joel Alves Rodrigues, Thales Nicolau Prímola-Gomes, Leôncio Lopes Soares, Tiago Ferreira Leal, Clara Nóbrega, [...]
Joel Alves Rodrigues, Thales Nicolau Prímola-Gomes, Leôncio Lopes Soares, Tiago Ferreira Leal, Clara Nóbrega, [...]
DOI: 10.5935/abc.20180113
Abstract Background: Regulation of intracellular calcium (Ca2+) in cardiomyocytes is altered by hypertension; and aerobic exercise brings benefits to hypertensive individuals. Objective: To verify the effects of aerobic exercise training on contractility and intracellular calcium (Ca2+) transients of cardiomyocytes and on the expression of microRNA 214 (miR-214) in the left ventricle of spontaneously hypertensive rats (SHR). Methods: SHR and normotensive Wistar rats of 16 weeks were divided into 4 groups -sedentary hypertensive (SH); trained hypertensive (TH); sedentary normotensive (SN); and […]
Keywords: Calcium Signaling; Exercise; Hypertension; Intracellular Calcium; Rats; Sensing Proteins
Bertha F. Polegato, Sergio A. R. de Paiva
DOI: 10.5935/abc.20180146
Abstract Background: Regulation of intracellular calcium (Ca2+) in cardiomyocytes is altered by hypertension; and aerobic exercise brings benefits to hypertensive individuals. Objective: To verify the effects of aerobic exercise training on contractility and intracellular calcium (Ca2+) transients of cardiomyocytes and on the expression of microRNA 214 (miR-214) in the left ventricle of spontaneously hypertensive rats (SHR). Methods: SHR and normotensive Wistar rats of 16 weeks were divided into 4 groups -sedentary hypertensive (SH); trained hypertensive (TH); sedentary normotensive (SN); and […]
Keywords: Exercise; Exercise Therapy; Hypertension/physiopathology; Hypertension/prevention & control; MicroRNAs/genetics; Molecular Targeted Therapy