Obesity is markedly linked to an increased risk of all-cause mortality and its prevalence has risen to unacceptable levels in the developed world., Obesity and insulin resistance compose the core of most cases of metabolic syndrome (MS), which is a group of conditions and traits associated with an increased risk of cardiovascular disease and diabetes (approximately 2-fold and 5-fold, respectively). Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of MS and has gained attention not only for obesity-related disorders […]

Arterial hypertension (AH) is frequently associated with metabolic disturbs, target-organs functional and/or structural alterations. In Brazil, it contributes, directly or indirectly, to 50% of cardiovascular disease death. AH experimental models have showed biochemical and cardiovascular alterations.– Among the most common experimental models of AH in rats are genetic hypertension developed by Okamoto and Aoki with the spontaneous hypertension model, Dahl salt-susceptible, a result of a defect in renal excrete sodium, neurogenic hypertension, defined as a permanent increase in blood pressure […]