A monthly publication of the Brazilian Society of Cardiology and considered the main channel for the promotion of Brazilian cardiovascular research.
ISSN 0066-782X
eISSN 1678-4170
Gustavo Augusto Ferreira Mota
, Mariana Gatto
, Claudia Maria Silva Cyrino, Silvio Assis de Oliveira Júnior, Marina Politi Okoshi
Gustavo Augusto Ferreira Mota
, Mariana Gatto
, Claudia Maria Silva Cyrino, Silvio Assis de Oliveira Júnior, Marina Politi Okoshi
Despite advances in cardiovascular medicine, heart disease is a serious public health problem due to its high prevalence, elevated cost, and high morbidity and mortality. Therefore, it is necessary to improve the understanding of molecular mechanisms involved in the pathophysiology of cardiovascular disease. Following cardiac injury, the heart undergoes a remodeling process, initially characterized by alterations in the genome expression. The changes lead to molecular, cellular, and interstitial modifications that manifest clinically as variations in the size, shape, and function […]
Keywords: Cardiovascular Diseases; Renin-Angiotensin System; Systems Biology; Ventricular Modeling; Ventricular Remodeling