Arq. Bras. Cardiol. 2022; 118(4): 783-786
Acute Myocarditis Following mRNA COVID-19 Vaccine
Daniel A. Gomes
, Rita R. Santos
, Pedro Freitas, Mariana S. Paiva, Jorge Ferreira
, Marisa Trabulo
Introduction
Vaccination is one of the most important breakthroughs of modern medicine and constitute a major advance in the prevention of infectious diseases. Overall, vaccines are effective and have an excellent general safety profile. In fact, reports of severe adverse effects following vaccination are extremely rare and idiosyncratic.
As the vaccine’s mechanism of action is based on the host immune response, a close relationship with autoimmunity cannot be disregarded. Cases of immunologic reactogenicity, such as Guillain-Barré syndrome and acute myocarditis following vaccination have been previously reported. ,
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