Arq. Bras. Cardiol. 2020; 115(6): 1193-1196
Emerging Topics in Heart Failure: Contemporaneous Management of Advanced Heart Failure
Fabiana G. Marcondes-Braga
, Jefferson L. Vieira
, João David de Souza Neto
, Gustavo Calado
, Silvia Moreira Ayub-Ferreira
, Fernando Bacal
, Nadine Clausell
Definition
Advanced heart failure (HF) is a condition characterized by persistent severe HF symptoms, frequent episodes of decompensation, and progressive cardiac dysfunction despite optimal evidence-based treatment. These patients may be candidates for advanced therapies, such as heart transplantation (HT), mechanical circulatory support (MCS), and/or palliative care. It should be pointed out that some comorbidities, including pulmonary disease and liver and kidney dysfunction, are now included as possible major determinants of poor prognosis and should be considered during patient evaluation for advanced HF therapies.
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