Arq. Bras. Cardiol. 2024; 121(3): e20230607
Intermittent Fasting in the Control of Hypertension: Do We Have Enough Evidence?
Adriana Camargo Oliveira
, Natália de Filippo Mariosa, Marcos Pereira Caetano, Mikaelle Costa Correia
Dear Editor,
The study published by Demirci et al. brings up an interesting and current discussion by evaluating the effect of intermittent fasting (IF) on blood pressure, the renin-angiotensin system (RAS), and the autonomic nervous system (ANS) in hypertensive patients using 24-hour ambulatory blood pressure monitoring (ABPM), Holter electrocardiogram, serum levels of Ang-I and Ang-II and ACE activity before and after IF. Among the findings was a notable reduction in blood pressure in patients undergoing IF, as well as a decreased expression of Ang-II and ACE in this same group. In addition, the reduction in Ang-II levels was identified as a predictive factor for blood pressure improvement after IF.
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Keywords: Arterial Stiffness; Blood Pressure; Fasting; Hypertension
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