Arq. Bras. Cardiol. 2025; 122(7): e20250153
Multiple Thrombotic Complications in a Patient With Polycythemia Vera
Barbara Zdzierak
, Bernadeta Chyrchel, Andrzej Surdacki, Stanisław Bartuś
, Artur Dziewierz
Introduction
Polycythemia vera (PV) is a rare Philadelphia chromosome–negative myeloproliferative neoplasm characterized by the clonal proliferation of multipotent bone marrow progenitor cells, leading to erythrocytosis and increased red blood cell mass. It may coexist with other hematologic disorders. PV results in blood hyperviscosity, which predisposes patients to thrombosis — the most common and clinically significant complication of PV. Post-PV myelofibrosis (post-PV MF) represents an advanced stage in the natural progression of PV. In patients with post-PV MF, thrombosis also remains one of the major complications. We present a case of multiple thrombotic events, namely acute coronary syndrome, digital arterial thrombosis, and ischemic stroke, in a patient with PV.
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Keywords: Myocardial Infarction; Polycythemia Vera; Thrombosis
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