Arq. Bras. Cardiol. 2023; 120(3): e20220234
Orthotopic Heart Transplantation in a Covid-19 Recipient
Leonardo Rufino Garcia
, André Monti Garzesi, Julia Bazzo Sinatora, Rejane Maria Tommasini Grotto, Andréia Cristina Passaroni, Nelson Leonardo Kerdahi Leite de Campos, Antônio Sérgio Martins, Marcello Laneza Felicio, Flávio de Souza Brito
Introduction
The coronavirus pandemic has affected more than 480 million people around the world. Solid organ recipients constitute a highly vulnerable group due to the need for immunosuppression and the various comorbidities that may be associated, many of which persist even after transplantation.
Transplanted patients can present a spectrum of clinical manifestations resulting from COVID-19: from asymptomatic, mild symptoms or acute respiratory failure and death. Some studies suggest that in the case of conditions with a favorable outcome, previous immunization and irreplaceable post-transplantation immunosuppression contribute to a response of less exacerbated inflammation and, consequently, less organic damage., Nonetheless, some reports and literature reviews show worse prognosis in transplanted patients, possibly due to comorbidities, advanced age, and lymphopenia often present.,,
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