Hypertension (HTN) is the most prevalent chronic disease in the entire world, being one of the most significant cardiovascular risks factors. Among several variables controlling blood pressure (BP), those directly interacting with neural mechanisms involve multiple areas of the central nervous system.
The relationship between brain activity and HTN has been demonstrated by neurophysiological studies on animals showing that direct electrical or chemical stimulation of different structures of the brainstorm and cerebral cortex can significantly modify BP and heart rate.–
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Transcranial Direct Current Stimulation in the Management of Hypertension: A Plausible Hypothesis?
ArêasFZS, KusterE, SouzaLC, DominguesWJR, SiqueiraJ, SerudoLHA, ArêasGP. Transcranial Direct Current Stimulation in the Management of Hypertension: A Plausible Hypothesis?. Arq. Bras. Cardiol. 2023;120(9):e20230100.
Arêas,Fernando Zanela da Silva; Kuster,Elizangela; Souza,Lenon Corrêa de; Domingues,Wagner Jorge Ribeiro; Siqueira,João; Serudo,Luíz Henrique Aquino; Arêas,Guilherme Peixoto. Transcranial Direct Current Stimulation in the Management of Hypertension: A Plausible Hypothesis?. Arq. Bras. Cardiol., v. 120, n. 9, e20230100, Sep. 2023.
Arêas,F.Z.S., Kuster,E., Souza,L.C. , Domingues,W.J.R., Siqueira,J., Serudo,L.H.A., & Arêas,G.P. (2023). Transcranial Direct Current Stimulation in the Management of Hypertension: A Plausible Hypothesis?. Arq. Bras. Cardiol.,120(9), e20230100.
Arêas,Fernando Zanela da Silva and Kuster,Elizangela and Souza,Lenon Corrêa de and Domingues,Wagner Jorge Ribeiro and Siqueira,João and Serudo,Luíz Henrique Aquino and Arêas,Guilherme Peixoto. Transcranial Direct Current Stimulation in the Management of Hypertension: A Plausible Hypothesis?. Arq. Bras. Cardiol. [online]. 2023, vol. 120, n. 9, [cited 2025-10-27], e20230100. Available from: <https://abccardiol.org/en/article/transcranial-direct-current-stimulation-in-the-management-of-hypertension-a-plausible-hypothesis/>. ISSN 0066-782X.