Abstract Background: Chronic kidney disease (CKD) is associated with a higher prevalence of valvular diseases and increased mortality from cardiovascular causes. Factors that influence the genesis of cardiac valve calcification (CVC) in these patients are not well-defined. Objective: To determine the risk factors for valvular calcification in patients with CKD. Methods: Systematic review based on PRISMA, which included observational studies evaluating the association of clinical and laboratory data with CVC in patients with CKD, undergoing or not hemodialysis or peritoneal […]

Abstract Targeted temperature management (TTM) is currently the only potentially neuroprotective intervention recommended for post-cardiac arrest care. However, there are concerns among the scientific community regarding conflicting evidence supporting this recommendation. Moreover, the bulk of trials included in systematic reviews that inform guidelines and recommendations have been conducted in developed countries, with case mix and patient characteristics that significantly differ from the reality of developing countries such as Brazil. Elevated body temperatures induce changes in the blood-brain barrier integrity and […]

Dear editor, The study published by Tang et al., entitled “Factors Affecting False Lumen Thrombosis in Type B Aortic Dissection,” highlighted the influence of morphological aspects of type B aortic dissection (TBAD), according to the Stanford classification, on false lumen thrombosis prior to treatment with endovascular repair of the thoracic aorta. It has been shown that false lumen thrombosis occurs significantly less frequently in patients with TBAD and renal failure, when compared with those with TBAD and normal renal function. […]

Abstract Background Machine Learning (ML) is a type of algorithm that autonomously learns to recognize complex patterns. In the diagnostic context of cardiac arrhythmias, these algorithms have shown significant advancements due to their ability to provide automated interpretation and pattern recognition in electrocardiograms (ECGs). Objective To analyze and identify the applicability, validity, and feasibility of ML algorithm models in the diagnostic process of cardiac arrhythmias through automated electrocardiogram interpretation. Methods This systematic literature review was reported according to the PRISMA […]

AI talks about the role of AI as a reviewer of medical papers: The peer review process is a cornerstone of scientific integrity, particularly in the field of medicine, where rigorous evaluation ensures that published research is credible, reproducible, and safe for clinical application. However, the growing volume of medical articles submitted for publication, coupled with the complexity of modern research, has strained the traditional peer review system. The use of AI in the peer review of medical articles represents […]

Abstract Background Physical activity (PA) plays a fundamental role in the prevention of type 2 diabetes mellitus (DM-2). However, findings regarding the influence of PA intensity on DM-2 over time remain inconsistent. Objective To examine the dose-response association between leisure-time PA intensity trajectories and DM-2. Methods The study included data from the Longitudinal Study of Adult Health (ELSA-Brasil), at baseline (2008-2010) and from 11 years’ follow-up, of 5777 women and 4590 men, aged from 35 to 75 years. Leisure-time PA […]

To Editor The early detection of asymptomatic atrial fibrillation (AF) is considered essential for preventing thromboembolic events and the progression of heart failure. Numerous wearable devices have been developed to facilitate this objective. The authors employed stroke risk analysis (SRA), a method that stratifies the risk of paroxysmal AF through the evaluation of electrocardiogram data. This algorithm proved effective in screening patients with asymptomatic paroxysmal AF, with 29.4% of participants categorized as high-risk. Among these high-risk individuals, AF was detected […]

Introduction Polycythemia vera (PV) is a rare Philadelphia chromosome–negative myeloproliferative neoplasm characterized by the clonal proliferation of multipotent bone marrow progenitor cells, leading to erythrocytosis and increased red blood cell mass. It may coexist with other hematologic disorders. PV results in blood hyperviscosity, which predisposes patients to thrombosis — the most common and clinically significant complication of PV. Post-PV myelofibrosis (post-PV MF) represents an advanced stage in the natural progression of PV. In patients with post-PV MF, thrombosis also remains […]

To the Editor, We read with great interest the article by Ternes et al., recently published in the Arquivos Brasileiros de Cardiologia, with its accompanying insightful editorial., This multicentre prospective cohort study of consecutive patients across three centres in Brazil provided valuable insights into the predictors of atrial arrhythmia recurrence following first-time catheter ablation. It highlighted its clinical setting in a middle-income country and reported outcomes similar to those in high-income countries. However, the results must be interpreted cautiously, and […]

June 2025 Issue, vol. 122(6):e20240586 In the Review Article “Direct Oral Anticoagulants versus Aspirin for Secondary Stroke Prevention in Patients with Embolic Stroke of Undetermined Source: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials”, with DOI: , published in the journal Arquivos Brasileiros de Cardiologia, Arq Bras Cardiol. 2025; 122(6):e20240586, on page 1, change the name of the author Thomas Costa Alexandre to: Thomaz Alexandre Costa. […]