Arq. Bras. Cardiol. 2023; 120(1): e20220902
Diabetes Mellitus, Physical Exercise and Heart Rate Variability
This Short Editorial is referred by the Research article "Effects of High-Intensity Interval Training and Continuous Training on Exercise Capacity, Heart Rate Variability and Isolated Hearts in Diabetic Rats".
The prevalence of diabetes mellitus (DM) has grown in recent decades. Risk factors for developing DM have been well established in clinical studies. Among these, sedentary lifestyles, aging and obesity stand out. DM, defined by increased plasma glucose concentration, is commonly accompanied by cardiovascular alterations such as hypertension, coronary disease, heart failure, and cardiac autonomic neuropathy. As cardiovascular diseases are currently the main causes of death and morbidity, studies aimed at better understanding the pathophysiological mechanisms inherent in DM are of great importance.
Cardiac autonomic neuropathy is characterized by changes in fibers that innervate the heart and blood vessels. , In this condition, changes in nerve function lead to reduced heart rate variability and altered baroreflex sensitivity.Physical exercise is considered an important non-pharmacological therapy to help prevent and control DM and its clinical consequences.Researchers have recently observed that exercise can also prevent and treat cardiac autonomic neuropathy.
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