Arq. Bras. Cardiol. 2020; 114(3): 476
Discordance of Low-Density Lipoprotein Cholesterol and Non-High-Density Lipoprotein Cholesterol with Severity of Coronary Artery Disease
Iran Castro
, Hugo Fontana Filho
This Short Editorial is referred by the Research article "Discordance of Low-Density Lipoprotein Cholestrol and Non-High-Density Lipoprotein Cholestrol and Coronary Artery Disease Severity".
Cardiovascular diseases (CVDs) are the leading cause of mortality world. Dyslipidemia is a risk and causal factor and is the focus of the therapy for primary and secondary prevention of CVDs.
There is consensus and broad understanding of the causal mechanisms of low-density lipoproteins (LDL) in CVDs, and the benefit of the hypolipidemic therapy, with a magnitude of effect proportional to the reduction in serum levels. However, despite intensive use of lipid lowering agents, there remains a residual risk, a constant target of research and therapy.
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