Arq. Bras. Cardiol. 2019; 113(4): 675-676
Evaluation of Serum Levels of Inflammation, Fibrinolysis and Oxidative Stress Markers in Coronary Artery Disease Prediction: A Cross-Sectional Study
Iran Castro
, Hugo Fontana Filho
DOI: 10.5935/abc.20190214
This Short Editorial is referred by the Research article "Evaluation of Serum Levels of Inflammation, Fibrinolysis and Oxidative Stress Markers in Coronary Artery Disease Prediction: A Cross-Sectional Study".
When assessing patients with coronary artery disease (CAD) traditional risk factors such as diabetes mellitus, hypertension, dyslipidemia, smoking, stress, physical inactivity, obesity, and family history are not found in 20% of the patients, and up to 40% of patients have only 1 risk factor. Considering the high prevalence of CAD and the fact that despite the numerous efforts made in primary prevention, the disease still has a high incidence, identifying markers that can predict at-risk patients is a goal that should always be pursued.
However, when evaluating a possible marker of disease, it must meet certain criteria. It should identify individuals at risk (accuracy), its results should be the same when repeated in other patients (reliability) and, especially, it should allow early intervention aiming at reducing the incidence of the problem (therapeutic impact).
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