Arq. Bras. Cardiol. 2025; 122(4): e20250185
Hypertrophic Cardiomyopathy in Brazil: Advances in Knowledge and Clinical Implications
Danielle Louvet Guazzelli, Mônica Samuel Avila
This Short Editorial is referred by the Research article "Clinical and Echocardiographic Particularities of Hypertrophic Cardiomyopathy in a Brazilian Population and its Prognostic Impact".
Hypertrophic cardiomyopathy (HCM) is the most prevalent genetically determined heart disease and remains a diagnostic and prognostic challenge. The estimated prevalence of this condition in the general population is approximately 1 case per 200 individuals. In Brazil, it is estimated that 400,000 people are affected.
The natural history of HCM is heterogeneous, with an unpredictable course that may manifest from childhood to the eighth decade of life. The disease also exhibits phenotypic heterogeneity, with two main clinical forms: left ventricular outflow tract obstruction (LVOTO) and non-obstructive.
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Keywords: Epidemiology; Hypertrophic cardiomyopathy; Prognosis
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