Arq. Bras. Cardiol. 2021; 117(6): 1104-1105
Searching Naturally Occurring Compounds to Treat Hypertension
Diego Santos Souza
, Danilo Roman-Campos
This Short Editorial is referred by the Research article "Antihypertensive Activity of Sauromatum guttatum Mediated by Vasorelaxation and Myocardial Depressant Effects".
Cardiovascular diseases (CDs) are the major cause of death worldwide. Impressively, approximately 17.9 million people died from CDs in 2019, representing almost 32% of global deaths. Also, nearly three-quarters of deaths due to CDs occur in low- and middle-income countries, which is a risk factor for Brazilians. There are several underlying mechanisms involved in CDs, and hypertension is a significant contributor. Today, it is thought that about 1.28 billion adults aged 30-79 years have hypertension in the world. Furthermore, it has been estimated that 60–70% of hypertension in adults is attributable to obesity, associated with insulin resistance, dyslipidemia and metabolic syndrome. Also, almost 50% of adults with hypertension are unaware of its condition, and only 20% have hypertension under control.
According to the American College of Cardiology and the American Heart Association, Normal Blood pressure (BP) is considering when Systolic Blood Pressure (SBP) is <120 mm Hg and < 80 mm Hg for diastolic blood pressure (DBP). Elevated BP is considered when SBP is 120-129, and DBP is <80 mg. Stage 1 and 2 hypertension are considering when SBP is 130-139 mm Hg or > 140 mm Hg, respectively, or DBP is 80-89 mm Hg or >90 mm Hg, respectively. These values follow the most recent Brazilian guideline to diagnostic hypertension.
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