Arq. Bras. Cardiol. 2021; 117(2): 279-280
Statin Associated With Physical Training: A Perfect Combination
Stephanie Bastos da Motta, Vanessa Caroline Toledes, Leandro Franzoni
This Short Editorial is referred by the Research article "Statin Use Improves Cardiometabolic Protection Promoted By Physical Training in an Aquatic Environment: A Randomized Clinical Trial".
Dyslipidemia and metabolic syndrome have grown exponentially over the recent years, including in children, mainly due to the low quality of food and the high level of a sedentary lifestyle.– These two diseases are important risk factors for the development of cardiovascular diseases. Reduction of low-density lipoprotein (LDL), as well as total cholesterol (TC) and the TC to high-density lipoprotein ratio (HDL – TC/HDL) are the main forms of cardiometabolic prevention. The use of statins is considered a standard treatment and the most effective pharmacological measure to improve the lipid profile. However, there are non-pharmacological alternatives that are also effective, one of which is physical exercise.
There is evidence on the importance of regular physical training as a form of primary or secondary prevention in the development or worsening of cardiometabolic diseases.– However, there is no consensus on the effect of combining statins with physical training, two powerful tools that, combined, can promote an even greater impact on the lipid profile. This is what the Costa et al. did in this edition of Arquivos Brasileiros de Cardiologia — they analyzed the influence of simvastatin on lipid adaptations resulting from aerobic and strength water training in elderly women with dyslipidemia. To this end, 69 female elderly sedentary dyslipidemic non-users and users of simvastatin (20 mg and 40 mg) (66.13±5.13 years) were analyzed.
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