Arq. Bras. Cardiol. 2021; 116(4): 742-743
Statin Use and Hypercholesterolemia: Are the Current Guidelines’ Recommendations Being Followed?
This Short Editorial is referred by the Research article "Statins Prescriptions and Lipid Levels in a Tertiary Public Hospital".
Despite advances in treating cardiovascular diseases, acute myocardial infarction and stroke are still the main causes of death worldwide.
The prevention of coronary atherosclerotic disease (CAD), represented by the treatment of low-density lipoprotein cholesterol (LDL-c), is one of the main alternatives for increasing the survival of patients with cardiovascular risk factors. Case-control, observational, and genetic studies confirm the importance of increased cholesterol level as one of the main modifiable risk factors for cardiovascular disease, especially for CAD and ischemic stroke. The reduction in LDL-c throughout life has been associated with a lower risk of developing CAD. There seems to be a causal relationship between LDL-c and CAD, which is continuous and which depends on the magnitude of the reduction in LDL-c.–
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